C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) C07K 14/74 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2190576
Chimeric MHC Classe I molecules having a recipient-type N-terminus, a donor-type alpha-1 helical region, and a recipient-type alpha-2 domain induce tolerance to donor grafts when administered to the recipient at time of transplantation.
Des molécules chimères de classe I du complexe majeur d'histocompatibilité présentant une extrémité N-terminale de type receveur, une région hélicoïdale alpha-1 de type donneur, et un domaine alpha-2 de type receveur induisent une tolérance à des greffes de donneurs lorsqu'on les administre aux receveurs au moment de la transplantation.
Ghobrial Rafik R.
Kahan Barry D.
Stepkowski Stanislaw M.
Kirby Eades Gale Baker
The Board Of Regents Of The University Of Texas System
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