Chimeric multivalent protein analogues and methods of use...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 7/08 (2006.01) C07K 14/705 (2006.01) C07K 16/00 (2006.01) C07K 16/42 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) C12N 9/00 (2006.01) C12N 15/62 (2006.01) G01N 33/531 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01) A61K 43/00 (1990.01) G06F 15/42 (1990.01)

Patent

CA 2135408

2135408 9323537 PCTABS00028 A chimeric immunoglobulin (Ig) Superfamily protein analogue comprising one or more polypeptide chains forming a .beta.-barrel domain having more than one biologically active binding site is disclosed. Also disclosed are methods of designing and producing chimeric multivalent Ig Superfamily protein analogues and compositions comprised of these analogues and methods of use thereof.

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