Chimeric oligonucleoside compounds

Details Chimeric oligonucleoside compounds Chimeric oligonucleoside compounds

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 31/70 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2176259

Chimeric oligonucleoside com- pounds and methods of preparing and formulating the same are disclosed. The compounds and compositions are useful in activating RNaseH-mediated cleavage of target ribonucleic acid se- quences and in treating disease condi- tions relating to such sequences.

Composés oligonucléosidiques chimériques et leurs procédés de préparation et de formulation. Ces composés et compositions sont utilisables dans l'activation du clivage à médiation par RNaseH des séquences cibles d'acide ribonucléique, et dans le traitement des états pathologiques associés à ces séquences.

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