Chimeric plasmid comprising a replicative retroviral genome...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/867 (2006.01) C07K 14/15 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 5/24 (2006.01) C12N 15/48 (2006.01)

Patent

CA 2445078

The invention concerns a chimeric plasmid comprising a replicative retroviral genome characterized in that it contains: a psi (.psi.)sequence, gag and pol sequences derived from a MLV virus genome, a chimeric env sequence including a region corresponding to part of the envelope derived from a MLV virus genome and a region corresponding to part of the envelope derived from a GaLV virus genome.

Plasmide comprenant un génome rétroviral réplicatif caractérisé en ce qu'il contient : une séquence psi ($G(C)), des séquences gag et pol provenant du génome d'un virus MLV, une séquence env chimère comprenant une région correspondant à une partie de l'enveloppe provenant du génome d'un virus MLV et une région correspondant à une partie de l'enveloppe provenant du génome d'un virus GaLV.

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