Chimeric proteins

Details Chimeric proteins Chimeric proteins

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) C07K 14/195 (2006.01) C07K 16/18 (2006.01) C07K 16/40 (2006.01) C12N 1/19 (2006.01) C12N 9/12 (2006.01) C12N 15/10 (2006.01) C12N 15/54 (2006.01) C12N 15/62 (2006.01) C12N 15/81 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2379165

The invention relates to a recombinant chimeric protein comprising a) a first domain with a nucleic acid synthesis activity and b) an interaction mediating sequence, whereby said interaction mediating sequence can form a complex through the nucleic acid synthesis activity and a slide bracketing protein. Said complex is different from the complex formed through the nucleic acid synthesis activity and/or the slide tying protein with their natural interaction partner(s).

L'invention concerne une protéine chimère recombinante comportant a) un premier domaine présentant une activité de synthèse d'acides nucléiques, et b) une séquence établissant une interaction. Cette séquence établissant une interaction permet de former un complexe par l'intermédiaire de l'activité de synthèse d'acides nucléiques et d'une protéine d'attache coulissante, ce complexe étant différent du complexe formé par l'intermédiaire de l'activité de synthèse d'acides nucléiques et/ou de la protéine d'attache coulissante et de leurs partenaires d'interaction naturels.

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