Chimeric proteins comprising yersinia yop, their preparation...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 38/16 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) A61P 37/02 (2006.01) C07K 14/21 (2006.01) C07K 14/24 (2006.01) C07K 14/705 (2006.01) C07K 19/00 (2006.01) C12N 5/00 (2006.01) C12N 15/18 (2006.01) C12N 15/28 (2006.01) C12N 15/31 (2006.01) C12N 15/63 (2006.01) C12N 15/79 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2603779

The present invention relates to a chimeric protein comprising a cell- targeting agent and a Yersinia outer protein, connected by a translocating polypeptide. The invention further relates to the preparation and use of such chimeric protein.

L'invention concerne une protéine chimère comprenant un agent de ciblage de cellule et une protéine extérieure Yersinia connectée au moyen d'un polypeptide de translocation. L'invention concerne également la préparation et l'utilisation de cette protéine chimère.

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