Chimeric proteins for cell targeting and apoptosis induction...

Details Chimeric proteins for cell targeting and apoptosis induction... Chimeric proteins for cell targeting and apoptosis induction...

C - Chemistry, Metallurgy

07

K

C07K 14/715 (2006.01) A61K 38/19 (2006.01) A61K 39/00 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2448100

Fusion proteins which comprise an apoptosis inducing protein portion and a cell targeting portion are disclosed. Fusion proteins which comprise a protease portion and a cell targeting portion are disclosed. Compositions for and methods of targeting and inducing the death of cells are disclosed.

L'invention concerne des protéines hybrides qui comprennent une fraction de protéine induisant apoptose et une fraction de ciblage cellulaire. L'invention concerne également des protéines hybrides qui comprennent une fraction protéase et une fraction de ciblage cellulaire. L'invention concerne en outre des compositions et des procédés permettant de cibler des cellules et d'induire la mort de celles-ci.

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