Chimeric pufa polyketide synthase systems and uses thereof

Details Chimeric pufa polyketide synthase systems and uses thereof Chimeric pufa polyketide synthase systems and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/52 (2006.01) A01H 5/00 (2006.01) C12N 9/00 (2006.01) C12N 15/82 (2006.01) C12P 7/64 (2006.01)

Patent

CA 2687523

Disclosed are chimeric polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) proteins and chimeric PUFA PKS systems, including chimeric PUFA PKS proteins and systems derived from Schizochytrium and Thraustochytrium. Disclosed are nucleic acids and proteins encoding such chimeric PUFA PKS proteins and systems, genetically modified organisms comprising such chimeric PUFA PKS proteins and systems, and methods of making and using such chimeric PUFA PKS proteins and systems.

L'invention concerne des protéines de polycétide synthase (PKS) d'acide gras polyinsaturé (PUFA) chimères et des systèmes de PKS de PUFA chimères, comprenant des protéines de PKS de PUFA chimères et des systèmes dérivés de Schizochytrium et Thraustochytrium. Sont décrits des acides nucléiques et des protéines codant pour de tels protéines de PKS de PUFA chimères et systèmes, des organismes génétiquement modifiés comprenant de tels protéines et systèmes de PKS de PUFA chimères, et des procédés de fabrication et d'utilisation de tels protéines et systèmes de PKS de PUFA chimères.

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