C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A01K 67/027 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2438119
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to a novel ecdysone receptor/chimeric retinoid X receptor-based inducible gene expression system and methods of modulating gene expression in a host cell for applications such as gene therapy, large-scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.
La présente invention concerne le domaine de la biotechnologie et du génie génétique. Cette invention concerne en particulier le domaine de l'expression génique et plus particulièrement un nouveau système d'expression de gène inductible fondé sur un récepteur X de rétinoïdes chimérique/récepteur d'ecdysone et des techniques de modulation de l'expression génique dans une cellule hôte en vue d'applications telles qu'une thérapie génique, la production à grande échelle de protéines et d'anticorps, des dosages de criblage à haut rendement à base de cellule, la génomique fonctionnelle et la régulation de traits dans des organismes transgéniques.
Kapitskaya Marianna Zinovjevna
Palli Subba Reddy
Gowling Lafleur Henderson Llp
Intrexon Corporation
Rheogene Holdings Inc.
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