Chimeric varicella zoster virus-virus like particles

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/01 (2006.01) A61K 39/145 (2006.01) A61K 39/25 (2006.01) A61K 39/295 (2006.01) A61P 31/12 (2006.01) A61P 37/04 (2006.01) C07K 14/04 (2006.01) C07K 14/11 (2006.01) C07K 19/00 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2693899

The present invention discloses novel chimeric Varicella Zoster Virus (VZV) virus-like parti-cles (VLPs) comprising chimeric VZV glycoproteins. The invention also discloses vaccine formulations of the chimeric VZV-VLPs and methods of inducing an immune re-sponse in subjects.

L'invention concerne de nouvelles pseudo-particules virales (VLP) du virus chimère de la varicelle et du zona (VZV) qui comprend des glycoprotéines VZV. Elle concerne également des formulations de vaccin des VLP du VZV chimère et des procédés destinés à induire une réponse immunitaire chez les patients.

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