Chimeric vegf peptides

Details Chimeric vegf peptides Chimeric vegf peptides

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 14/475 (2006.01) C07K 19/00 (2006.01) C12N 15/18 (2006.01)

Patent

CA 2555274

Compositions for and methods of treating patients with malignancies associated with overexpression of VEGF, particularly ovarian cancer. The compositions include but are not limited to certain VEGF epitopes, multivalent peptides comprising said epitopes, and chimeric peptides comprising one or more of said epitopes and a T cell epitope.

L'invention concerne des compositions et des méthodes de traitement de patients atteints de tumeurs malignes liées à la surexpression du VEGF, en particulier le cancer de l'ovaire. Ces compositions contiennent, entre autres, certains épitopes du VEGF, des peptides multivalents contenant lesdits épitopes, ainsi que des peptides chimériques contenant au moins un desdits épitopes et un épitope de lymphocyte T.

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