Chiral 2-(phosphonomethoxy)propyl guanines as antiviral agents

C - Chemistry – Metallurgy – 07 – F

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C07F 9/6561 (2006.01) A61K 31/675 (2006.01)

Patent

CA 2040854

The present invention provides a chiral nucleotide analog having the formula I (see formula I) which is substantially free of the (S)-isomer and pharmaceutically acceptable salts and solvates thereof, and their pharmaceutical compositions, which is useful in the treatment of viral infections, especially those caused by human immunodeficiency virus (HIV).

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