Chiral compounds and their resolution

Details Chiral compounds and their resolution Chiral compounds and their resolution

C - Chemistry, Metallurgy

12

P

C12P 41/00 (2006.01) C07C 255/41 (2006.01) C07D 211/88 (2006.01) C07D 213/57 (2006.01) C07D 401/04 (2006.01) C12P 17/12 (2006.01)

Patent

CA 2191363

Enantiomeric glutarimides such as aminoglutethimide and rogletimide are prepared by cyclisation of a corresponding ester-nitrile which is a good substrate for biotransformation with an enantiospecific esterase.

On prépare des glutarimides énantiomères tels que l'aminoglutéthimide et le roglétimide par cyclisation d'un ester-nitrile correspondant constituant un bon substrat pour la biotransformation à l'aide d'une estérase énantiospécifique.

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