Chiral fluoroquinolizinone arginine salt forms

Details Chiral fluoroquinolizinone arginine salt forms Chiral fluoroquinolizinone arginine salt forms

C - Chemistry, Metallurgy

07

D

C07D 455/04 (2006.01) A61K 31/4375 (2006.01) A61K 45/06 (2006.01) A61P 31/00 (2006.01) C07C 279/14 (2006.01) C07D 215/233 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 471/04 (2006.01) C07D 471/08 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2403264

The invention relates to the new arginine salt forms of S-(-)-9-fluoro-6,7- dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine- 2-carboxylic acid, a process for their preparation and pharmaceutical formulations which comprise those arginine salt forms as the active ingredient for its use in treating antimicrobial infections.

Cette invention se rapporte à des formes sels d'arginine nouvelles d'acide S-(-)-9-fluoro-6,7-dihydro-8-(4-hydroxypipéridine-1-yl)-5-méthyle-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylique, à un procédé de préparation de ces nouvelles formes et à des formulations pharmaceutiques qui comprennent ces nouvelles formes sels d'arginine comme principe actif, à utiliser dans le traitement d'infections antimicrobiennes.

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