Chiral integrin modulators and methods of use thereof

Details Chiral integrin modulators and methods of use thereof Chiral integrin modulators and methods of use thereof

C - Chemistry, Metallurgy

07

C

C07C 321/12 (2006.01) C07C 321/18 (2006.01) C07C 323/65 (2006.01)

Patent

CA 2415985

The invention provides enantiomers of ajoene and derivtives of Z(-)-ajoene. The derivative of Z(-)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.

L'invention concerne des énantiomères d'ajoene et des dérivés de Z(-)-ajoene. Ces dérivés de Z(-)-ajoene sont utiles pour moduler les fonctions induites par les intégrines, pour traiter des troubles, maladies ou pathologies, dans lesquels les intégrines jouent un rôle, et pour traiter des tissus aux fins d'amélioration de l'état de ceux-ci, en vue d'une utilisation ultérieure, telle qu'une transplantation.

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