Chiral organoboranes

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 5/02 (2006.01) C07C 29/143 (2006.01) C07C 209/52 (2006.01) C07D 491/04 (2006.01) C07D 491/056 (2006.01)

Patent

CA 2257678

Chiral organoboranes of general formulae (I) and (II), wherein each of R¿1? and R¿2?, which are the same or different, is a hydrogen atom or an alkyl or cycloalkyl radical, or R¿1? and R¿2?, taken together, are a saturated divalent hydrocarbon grouping; X¿1? is a hydrogen atom; and X¿2? is a hydrogen or halogen atom; are disclosed. Methods for preparing such compounds, and the use thereof, particularly as an asymmetrical reducing agent, are also disclosed.

L'invention concerne des organoboranes chiraux de formules générales (I et II) dans lesquelles soit R1 et R2 représentent, indépendamment, un atome d'hydrogène ou un radical alkyle ou cycloalkyle, soit R1 et R2 représentent ensemble un groupement hydrocarboné divalent saturé; X1 représente un atome d'halogène; et X2 représente un atome d'hydrogène ou d'halogène. L'invention concerne également des procédés pour leur préparation et leur utilisation notamment en tant qu'agent de réduction asymétrique.

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