Chiral phosphorus compounds

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 9/53 (2006.01) C07F 9/36 (2006.01)

Patent

CA 2567939

A process for the stereoselective preparation of a P-chiral four-co-ordinated phosphorus compound, the process comprising reacting a first reactant selected from the group consisting of a chiral alcohol, chiral amine or chiral thiol, with a second reactant comprising a P-chiral three-co-ordinated phosphorus compound, in the presence of an electrophile.

L'invention concerne un procédé de préparation stéréosélective d'un composé phosphoré tétracoordiné P-chiral, lequel procédé consiste à faire réagir un premier réactif, sélectionné dans le groupe constitué par un alcool chiral, une amine chirale ou un thiol chiral, avec un second réactif comprenant un composé phosphoré tricoordiné P-chiral, en présence d'un électrophile.

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