C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/270, 260/325
C07D 471/08 (2006.01) C07D 207/16 (2006.01) C07D 487/08 (2006.01) C07D 491/04 (2006.01) C07D 491/044 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2016706
ABSTRACT Title: CHIRAL SYNTHESIS FOR PRODUCING 1-AZABICYCLO[2.2.1] HEPTANE-3-CARBOXYLATES A process for preparing substantially pure enantiomers of formula (I) Image (I) where the * represents a chiral centre, x is 0 or 1, in exo-, endo- or a mixture of exo- and endo- forms; and R is hydrogen, alkyl or aralkyl, via diastereomers of formula (IIA) or (IIB): Image Image IIA IIB
Cottrell Ian F.
Hands David
Wright Stanley H.b.
Cottrell Ian F.
Hands David
Merck Sharp & Dohme Limited
Swabey Ogilvy Renault
Wright Stanley H.b.
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