Chiral synthesis of 2-hydroxy carboxylic acids with a...

Details Chiral synthesis of 2-hydroxy carboxylic acids with a... Chiral synthesis of 2-hydroxy carboxylic acids with a...

C - Chemistry, Metallurgy

12

N

C12N 15/52 (2006.01) C12N 9/04 (2006.01) C12P 7/42 (2006.01)

Patent

CA 2193984

Inter alia, an enzyme, a 2-hydroxy carboxylic acid dehydrogenase, characterised in that it is obtainable from Lactobacillus delbrueckii ssp. Bulgaricus and in that it catalyses the production of (R)-hydroxy derivatives of 2-keto acids, which are unsubstituted in the 3-position, but which may be substituted in the 4-position or beyond is disclosed.

L'invention concerne notamment une enzyme, une acide 2-hydroxycarboxylique-déshydrogénase, caractérisée en ce qu'elle est obtenue à partir de Lactobacillus delbrueckii ssp. Bulgaricus et en ce qu'elle catalyse la production de dérivés de (R)-hydroxy de 2-céto-acides, qui sont non substitués dans la position 3, mais qui peuvent être substitués dans la position 4 ou au-delà.

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