Chiral two-phase system and method for resolution of racemic...

Details Chiral two-phase system and method for resolution of racemic... Chiral two-phase system and method for resolution of racemic...

C - Chemistry, Metallurgy

07

C

252/18, 260/323,

C07C 215/60 (2006.01) C07D 209/20 (2006.01)

Patent

CA 1281335

ABSTRACT A chiral two-phase system for resolution of racemic mixtures, or for separation of diastereomers, is dis- closed. The system comprises two immiscible liquid phases and one or more enantioselectively binding chiral components, each of which is substantially in one of said phases. Also disclosed is a method for chiral resolution of racemic mixtures, or for separation of diastereo- mers. Use is here made of the fact that different enantiomers are partitioned differently between the phases in the above-mentioned two-phase system in that one of the enantiomers is selectively bound to one of the chiral components which is substantially in one of said phases.

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