Chitosan carboxyalkylamide hydrogel, preparation thereof and...

A - Human Necessities – 61 – K

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A61K 8/02 (2006.01) A61K 8/73 (2006.01) A61K 9/06 (2006.01) A61K 9/19 (2006.01) A61K 31/722 (2006.01) A61K 36/28 (2006.01) A61P 17/02 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2693644

The present invention relates to a chitosan carboxyalkylamide hydrogel, characterized in that it has a pH value close to that of skin, between 6.5 and 7.2, and in that the chitosan carboxyalkylamide comprises from 40 to 90 mol% of D-glucosamine N-carboxyalkylamide units of formula (I) where n is an integer ranging from 1 to 8, from 60 to 10 mol% of protonated D-glucosamine units, and from 5 to 15 mol% of N-acetyl-D-glucosamine units. The present invention also relates to a product of dehydration of such a gel and to the cosmetic and/or dermatological use of the gel and of the dehydration product.

La présente invention concerne un hydrogel de carboxyalkylamide de chitosan, caractérisé par le fait qu'il présente une valeur de pH proche de celui de la peau, compris entre 6,5 et 7,2, et par le fait que le carboxyalkylamide de chitosan est constitué de 40 a 90 % en moles de motifs N-carboxyalkylamide de D-glucosamine de formule (I) où n représente un nombre entier allant de 1 à 8, de 60 à 10 % en moles de motifs D-glucosamine protonés, et de 5 à 15 % en moles de motifs N-acétyl-D- glucosamine. La présente invention concerne également un produit de déshydratation d'un tel gel et l'utilisation cosmétique et/ou dermatologique du gel et du produit de déshydratation.

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