Chlamydia antigens and corresponding dna fragments and uses...

Details Chlamydia antigens and corresponding dna fragments and uses... Chlamydia antigens and corresponding dna fragments and uses...

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 31/70 (2006.01) A61K 39/118 (2006.01) C07K 14/295 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2348958

In summary of this disclosure, the present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector, containing a nucleotide sequence encoding a 98 kDa putative outer membrane protein of a strain of Chlamydia pneumoniae and a promoter to effect expression of the 98 kDa putative outer membrane protein gene in the host. Modifications are possible within the scope of this invention.

En résumé de cette divulgation, la présente invention a trait à une méthode d'immunisation d'un hôte par l'acide nucléique, notamment l'ADN, y compris des sujets humains, contre une maladie provoquée par une infection par une souche de chlamydia, spécifiquement C. pneumoniae, employant un vecteur, contenant une séquence de nucléotides codant une protéine de membrane extérieure putative de 98 kDa d'une souche de Chlamydia pneumoniae ainsi qu'un promoteur afin de procéder à l'expression du gène de la protéine de membrane extérieure putative de 98 kDa chez l'hôte. Des modifications sont possibles dans le champ d'action de cette invention.

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