Chlamydia antigens and corresponding dna fragments and uses...

Details Chlamydia antigens and corresponding dna fragments and uses... Chlamydia antigens and corresponding dna fragments and uses...

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/02 (2006.01) A61K 48/00 (2006.01) C07K 14/295 (2006.01) C07K 16/12 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2348960

In summary of this disclosure, the present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector, containing a nucleotide sequence encoding an PilG-like protein of a strain of Chlamydia pneumoniae and a promoter to effect expression of the PilG-like gene in the host. Modifications are possible within the scope of this invention.

En résumé de cette divulgation, la présente invention concerne une méthode d'immunisation d'un hôte par l'acide nucléique, notamment l'ADN, y compris des sujets humains, contre une maladie provoquée par une infection par une souche de chlamydia, spécifiquement C. pneumoniae, employant un vecteur, contenant une séquence de nucléotide codant une protéine de type PilG d'une souche de Chlamydia pneumoniae ainsi qu'un promoteur pour procéder à l'expression du gène de type PilG chez l'hôte. Des modifications sont possibles dans le champ d'action de cette invention.

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