Chlamydia antigens and corresponding dna fragments and uses...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/118 (2006.01) A61K 31/7088 (2006.01) C07K 14/295 (2006.01) C12N 15/31 (2006.01) C12N 15/85 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C07K 16/12 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2385325

The present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia specifically C. pneumoniae, employing a vector containing a nucleotide sequence encoding OMP (outer membrane protein) of a strain ofChlamydia pneumoniae and a promoter to effect expression of the OMP (outer membrane protein) gene in the host. Modifications are possible within the scope of this invention.

La présente invention concerne une méthode d'immunisation par acide nucléique, y compris l'ADN, d'un hôte, y compris un hôte humain, contre les maladies causées par une infection provoquée par une souche de Chlamydia en particulier de C. pneumoniae, et ce, à l'aide d'un vecteur contenant une séquence nucléotidique codant pour une OMP (protéine de membrane externe) d'une souche de Chlamydia pneumoniae, et d'un promoteur d'expression du gène de l'OMP (protéine de membrane externe) dans l'hôte. Des modifications de l'invention sont possibles.

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