Chlamydia antigens and corresponding dna fragments and uses...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/118 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) C07K 14/295 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/31 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) A61K 48/00 (2006.01) C07K 16/12 (2006.01)

Patent

CA 2395499

The present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector containing a nucleotide sequence encoding an omp P6 precursor of a strain of Chlamydia pneumoniae and a promoter to effect expression of the omp P6 precursor in the host. Modifications are possible within the scope of this invention.

La présente invention concerne un procédé d'immunisation par acide nucléique, notamment par ADN, d'un hôte, notamment d'un être humain, contre des maladies induites par une infection par une souche de Chlamydia, plus particulièrement de C. pneumoniae, au moyen d'un vecteur contenant une séquence nucléotidique qui code un précurseur omp P6 d'une souche de Chlamydia pneumoniae et un promoteur d'expression du précurseur omp P6 dans l'hôte. Des modifications sont envisageables dans le cadre de l'invention.

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