C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/118 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/295 (2006.01) C07K 16/12 (2006.01) C12N 15/11 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2353107
The present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically C. pneumoniae, employing a vector containing a nucleotide sequence encoding a 98 kDa outer membrane protein of a strain of Chlamydia pneumoniae and a promoter to effect expression of the 98 kDa outer membrane protein gene in the host. Modifications are possible within the scope of this invention.
La présente invention concerne un procédé d'immunisation par acides nucléiques (y compris par ADN) d'hôtes (y compris les humains) contre les maladies provoquées par l'infection par une souche de Chlamydia, notamment de C. pneumoniae, au moyen d'un vecteur contenant une séquence nucléotidique contenant une protéine de membrane extérieure de 98 kDa appartenant à la souche de C. pneumoniae et un promoteur assurant l'expression chez l'hôte du gène de la protéine de membrane extérieure de 98 kDa. Des modifications sont possibles dans le cadre de cette invention.
Dunn Pamela
Murdin Andrew D.
Oomen Raymond P.
Wang Joe
Aventis Pasteur Limited
Smart & Biggar
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