Chlamydia heat shock protein

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) C07K 14/00 (2006.01) C07K 14/295 (2006.01) C12N 15/31 (2006.01) C12N 15/63 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2435054

An expression system for production of full-length Chlamydial heat shock protein 60 (CHSP60) and an immunoreactive subfragment thereof is described. The expression system is arranged such that the CHSP60 or fragment is initially isolated as a fusion protein which is then cleaved off, leaving purified CHSP60.

L'invention concerne un système d'expression permettant de produire une protéine de choc thermique pleine longueur de chlamydia 60 (CHSP60) et un sous-fragment immunoréactif de cette protéine. Ce système d'expression est conçu de sorte que la CHSP60 ou son fragment soient initialement isolés sous forme de protéine de fusion, laquelle est ensuite clivée, laissant une CHSP60 purifiée.

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