Chlamydia pneumoniae genome sequence

Details Chlamydia pneumoniae genome sequence Chlamydia pneumoniae genome sequence

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) C07K 14/295 (2006.01) C07K 16/12 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2350775

<i>C. pneumoniae</i> genome sequence and analysis of the encoded polypeptides and RNAs are provided. The <i>C. pneumoniae</i> gene nucleic acid compositions find use in identifying homologous or related proteins and the DNA sequences encoding such proteins; in producing compositions that modulate the expression or function of the protein; and in studying associated physiological pathways. In addition, modulation of the gene activity <i>in vivo</i> is used for prophylactic and therapeutic purposes, such as identification of cell type based on expression, and the like.

L'invention concerne la séquence génomique de <i>Chlamydia pneumoniae</i> et l'analyse des polypeptides et des ARN codés. Les compositions d'acide nucléique du gène de <i>Chlamydia pneumoniae</i> permettent d'identifier des protéines homologues ou associées ainsi que les séquences d'ADN codant pour ces protéines, de produire des compositions modulant l'expression ou la fonction de la protéine, et d'étudier les mécanismes physiologiques associés. En outre, la modulation de l'activité génique <i>in vivo</i> est utilisée à des fins prophylactiques et thérapeutiques, telles que l'identification du type cellulaire sur la base de l'expression et analogues.

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