A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/118 (2006.01) C07K 14/295 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2280037
Immunogenic compositions including vaccines are described that comprise an outer membrane antigen extract of a strain of Chlamydia and are effective in protection against disease caused by Chlamydia infection. The immunogenic compositions may comprise the major outer membrane protein (MOMP) of Chlamydia which may be in a homooligomeric form or complexed with at least one other antigen of Chlamydia. The immunogenic composition may include an immunostimulating complex (ISCOM) and the outer membrane antigen may be incorporated therein. The immunogenic compositions have utility as chlamydial vaccines and in diagnostic applications.
La présente invention décrit des compositions immunogènes comprenant des vaccins comportant un extrait antigène de membrane d'une souche de chlamydiae utilisable dans la prophylaxie des infections causées par les chlamydiae. Lesdites compositions immunogènes peuvent contenir la protéine de la membrane externe principale de chlamydia sous forme isooligomérique, ou complexé avec au moins un autre antigène de chlamydia. Ladite composition immunogène peut comprendre un complexe immunostimulant auquel l'antigène de membrane externe peut être incorporé. Ces compositions servent de vaccins anti-chlamidiae et pour certaines applications de diagnostic.
Murdin Andrew D.
Underdown Brian J.
Connaught Laboratories Limited
Sanofi Pasteur Limited/sanofi Pasteur Limitee
Yacoob Reza K.
LandOfFree
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