A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/715 (2006.01) A23L 1/30 (2006.01) A61P 1/10 (2006.01) A61P 17/02 (2006.01) A61P 37/02 (2006.01) A61K 35/80 (2000.01)
Patent
CA 2354832
Chlorella extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combination of: galactose, rhamnose, mannose and arabinose, as well as N-acetyl glucosamine and N-acetyl galactosamine. The extracts may be treated with pronase, DNAse, RNAse and proteases to remove unassociated nucleic acids, ribonucleic acids and proteins. The extracts may also undergo treatment to effect cleavage of specific glycosidic linkages, the linkages being defined by their susceptibility to cleavage by amylase, amyloglucosidase, cellulase or neuraminidase. Chlorella extracts may be administered to a mammal to increase proliferation of splenocytes and increase production of cytokines such as IL-6, IL-10, INF-.gamma. and TNF-.alpha.. They may be used as a supplement to a vaccination regimen.
Ocean Nutrition Canada Limited
Ocean Nutrition Canada Ltd.
Smart & Biggar
LandOfFree
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