Chlorhexidine monophosphanilate and process for selectively...

C - Chemistry – Metallurgy – 07 – C

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260/543.4

C07C 129/16 (1985.01)

Patent

CA 1215387

0244H Abstract of the Disclosure A water soluble salt of chlorhexidine is mixed with a water soluble salt containing phosphanilate mono-anion when chlorhexidine diphosphanilate is desired, or with a water soluble salt containing phosphanilate di-anion when chlorhexidine monophosphanilate is desired. The desired mono- or di-phosphanilate salt of chlorhexidine precipitates and is selectively recovered. Chlorhexidine monophos- phanilate is a novel salt having antibacterial activity substantially comparable to that of chlorhexidine diphosphanilate.

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