Chlorhexidine salts and compositions of same

A - Human Necessities – 61 – K

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167/231, 167/241

A61K 31/44 (2006.01) A61K 31/155 (2006.01)

Patent

CA 1175356

Abstract: The dinalidixate and diphosphanilate salts of chlorhexidine possess antibacterial activity. They exhibit synergism as compared with comparable concentrations of chlorhexidine and the respective free acid. Synergistic compositions comprising a mixture of a chlorhexidine salt with phosphanilic acid or a salt of phosphanilic acid, or with nalidixic acid, or a salt of nalidixic acid are disclosed. Dermatological compositions of such novel salts, and all such mixtures, are provided.

387001

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