Chlorite in the treatment of neurodegenerative disease

A - Human Necessities – 61 – K

Patent

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Details

A61K 33/00 (2006.01) A61K 33/14 (2006.01) A61K 33/40 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2554511

The invention features methods of treating a macrophage-associated neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), or multiple sclerosis (MS) in a subject by administering chlorite in an amount effective to decrease blood immune cell activation. The invention also features methods of monitoring therapy by assessing blood immune cell activation before and after therapy.

La présente invention a trait à des procédés de traitement d'une maladie neurodégénérative associée aux macrophages telles que la sclérose latérale amyotrophique, la maladie d'Alzheimer, ou la sclérose en plaques chez un sujet par l'administration de chlorite en une quantité efficace pour réduire l'activation de cellules immunitaires sanguines. L'invention a également trait à des procédés pour un suivie de thérapie par l'évaluation de l'activation des cellules immunitaires sanguines avant et après le traitement.

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