Chlorofluorocarbon-free mometasone furoate aerosol formulations

Details Chlorofluorocarbon-free mometasone furoate aerosol formulations Chlorofluorocarbon-free mometasone furoate aerosol formulations

A - Human Necessities

61

K

A61K 31/58 (2006.01) A61K 9/12 (2006.01) A61K 9/72 (2006.01)

Patent

CA 2263905

The invention relates to suspension aerosol formulations which exhibit stable particle sizes, containing mometasone furoate, about 1 to about 10 weight percent ethanol and 1,1,1,2,3,3,3-Heptafluoropropane as the propellant. A surfactant, such as oleic acid, can also be included. These formulations are suitable for use in metered dose inhalers.

La présente invention concerne des formulations pour suspensions d'aérosols, lesquelles formulations font preuve d'une stabilité des tailles particulaires, et contiennent du mométazone furoate, environ 1 % à environ 10 % en masse d'éthanol et du 1,1,1,2,3,3,3-heptafluoropropane comme propulseur. Il est également possible d'ajouter un agent tensio-actif tel que l'acide oléique. Ces formulations conviennent particulièrement aux aérosols-doseurs.

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