Cholestanol derivative for combined use

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/704 (2006.01) A61K 31/282 (2006.01) A61K 31/337 (2006.01) A61K 31/519 (2006.01) A61K 31/7072 (2006.01) A61K 33/24 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07J 9/00 (2006.01)

Patent

CA 2754075

The invention provides a cancer chemotherapeutic agent which has fewer side effects and excellent efficacy. The cancer chemotherapeutic agent of the invention includes a cholestanol derivative represented by formula (1): (see formula 1) (wherein G represents GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal-, or GlcNAc-) or a cyclodextrin inclusion compound thereof, and an anti-cancer agent.

La présente invention concerne un agent chimiothérapeutique contre le cancer ayant des effets indésirables moindres et une excellente efficacité. L'agent chimiothérapeutique contre le cancer comprend une combinaison d'un dérivé du cholestanol représenté par la formule générale (1) [dans laquelle G représente GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal- ou GlcNac-] ou un composé d'inclusion cyclodextrine de celui-ci et un agent anticancéreux.

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