Cholesterol as an antibiotic for streptococcus pneumoniae

Details Cholesterol as an antibiotic for streptococcus pneumoniae Cholesterol as an antibiotic for streptococcus pneumoniae

A - Human Necessities

61

K

A61K 31/56 (2006.01)

Patent

CA 2602855

Topical application of cholesterol has been found to be effective in preventing, treating or ameliorating the damage to the cornea caused by Streptococcus pneumoniae. Topical administration of cholesterol caused a significant decrease in the inflammation of the eye. In addition, cholesterol was surprisingly found to be a bactericide to Streptococcus pneumoniae outside the cornea. The effect of cholesterol can be enhanced by further administering a steroid or an antibiotic to the cornea.

On a découvert qu~une application locale de cholestérol est efficace pour la prévention, le traitement ou l~amélioration des dommages à la cornée provoqués par Streptococcus pneumoniae. Une administration locale de cholestérol provoque une diminution significative de l~inflammation de l~oeil. De plus, on a découvert de façon surprenante que le cholestérol est un bactéricide pour Streptococcus pneumoniae à l~extérieur de la cornée. L~effet du cholestérol peut être amélioré en administrant en plus un stéroïde ou un antibiotique à la cornée.

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