Chromane derivatives as trpv3 modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 311/96 (2006.01) A61K 31/353 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2706566

The present invention provides transient receptor potential vanilloid (TRPV) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPV3. Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPV3.

L'invention concerne des modulateurs des récepteurs transitoires à potentiel vanilloïde (TRPV). Les composés selon l'invention sont en particulier utiles pour traiter ou prévenir des maladies, états et/ou troubles modulés par TRPV3. L'invention porte également sur des procédés de préparation desdits composés, sur des intermédiaires utilisés dans leur synthèse, sur des compositions pharmaceutiques les renfermant, et sur des procédés permettant de traiter ou prévenir des maladies, états et/ou troubles modulés par TRPV3.

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