Chromane derivatives, process for their preparation and...

Details Chromane derivatives, process for their preparation and... Chromane derivatives, process for their preparation and...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/415 (2006.01) A61K 31/4155 (2006.01) A61K 31/47 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2434066

Compounds which are chromane derivatives of formula (I), pharmaceutically acceptable salts, process for their preparation and pharmaceutical compositions thereof are disclosed, as set forth in the specification; these compounds are useful in therapy in the treatment of cell proliferative disorders, e.g. cancer, associated with an altered cell cycle dependent kinase activity.

La présente invention concerne des composés qui sont des dérivés de chromane représentés par la formule (I), des sels pharmaceutiquement acceptables, des procédés permettant de les préparer ainsi que des compositions pharmaceutiques, tels que définis dans le descriptif. Ces composés sont utiles à des fins thérapeutiques pour traiter des troubles de prolifération cellulaire, tels que le cancer, associés à une activité kinase modifiée dépendant du cycle cellulaire.

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