Chromanone derivatives

Details Chromanone derivatives Chromanone derivatives

C - Chemistry, Metallurgy

07

D

C07D 311/22 (2006.01)

Patent

CA 2421287

The invention relates to chromanone derivatives of formula (I) wherein R1 to R4 respectively and independently represent H, A, CH, Hal, OR5, COOR5, CH3, OCF3, NO2, Ar, Oar, N(R5)2 or CON(R5)2; R5 represents H or A, A represents an alkyl comprising 1 to 6 C atoms; Ar represents an unsubstituted phenyl or a phenyl substituted by A, OR5, Cn Hal, CF3, OCF3, NO2 or N(R5)2; and Hal represents F, Cl, Br or I. The invention also relates to the salts thereof. Said derivatives and salts are suitable as intermediate products in the synthesis of pharmaceuticals.

L'invention concerne des dérivés de chromanone de formule (I) dans laquelle, R?1¿ à R?4¿ désignent, indépendamment l'un de l'autre H, A, CH, Hal, OR?5¿, COOR?5¿, CH?3¿, OCF?3¿, NO?2¿, Ar, Oar, N(R?5¿)¿2? ou CON(R?5¿)¿2?, R?5¿ désigne H ou A, A désigne un alkyle de 1 à 6 atomes de C, Ar désigne un phényle non substitué, ou substitué par A, OR?5¿, Cn Hal, CF¿3?, OCF¿3?, NO¿2? ou N(R?5¿)¿2?, Hal désigne F, Cl, Br ou I. L'invention concerne également des sels de ces dérivés. Les dérivés et leurs sels conviennent comme produits intermédiaires pour la synthèse de médicaments.

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