Chromatographic apparatus and method

B - Operations – Transporting – 01 – D

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B01D 15/08 (2006.01) B01D 15/18 (2006.01) G01N 30/44 (2006.01) G01N 30/46 (2006.01) G01N 30/24 (2006.01)

Patent

CA 1132371

ABSTRACT OF THE DISCLOSURE An apparatus and method for increasing the throughput of a chromatographic system by passing several samples in seriatim through tandemly connected first and second chromatographic columns. The eluant from the first column is sampled, or fractionated, and fractions of each of the samples are passed through the second column for further separation. A switching of the sampling valve, disposed between the first and second columns, effects such fractioning. The pumping rate for the second column may be different from that of the first column and allows that two or more sample fractions can occupy the second column concurrently. Docket 2120-A -1-

321124

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