Chromatographic purification process

Details Chromatographic purification process Chromatographic purification process

C - Chemistry, Metallurgy

12

N

195/78

C12N 1/00 (2006.01) C07K 3/18 (1990.01)

Patent

CA 1315229

X-6747 M ABSTRACT This invention relates to a new chromatog- raphic process for purifying fermentation products, particularly the antibiotic LY146032, from fermentation broths by use of a reverse phase non-functional resin. In the process of this invention the resin is loaded with the compound in the aqueous phase, the water then is removed from the resin and the resin converted to the organic phase for the resolution step. This process is applicable to purifying compounds which are adsorbed on reverse phase non- functional resins.

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