Chromatography columns and their operation

B - Operations – Transporting – 01 – D

Patent

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Details

B01D 15/08 (2006.01) G01N 30/60 (2006.01)

Patent

CA 2547769

A method of operating chromatography column apparatus comprising a column tube (101) and first and second discrete end cell structures, associated with the respective ends of the column tube and positionable to close off the column tube and define therein a column space for retaining chromatography medium in use of the apparatus. The first end cell portion comprises a piston portion (106) fitting slidably in the column tube. The column tube and the second end cell structure are separated to provide an access spacing between them. The piston portion (106) of the first end cell structure is advanced through the column tube to expose it at the open second end of the column tube, for maintenance of the piston portion thus exposed. Corresponding chromatography apparatus is another aspect of the disclosure.

L'invention concerne un procédé d'utilisation d'un dispositif à colonne de chromatographie comportant un tube de colonne (101) et une première et une deuxième structure à cellule terminale discrète, associées aux extrémités respectives du tube de colonne et pouvant être disposées de manière à fermer le tube de colonne et former un espace de colonne destiné à contenir du fluide chromatographique utilisé dans le dispositif. La première partie à cellule terminale comporte une partie piston (106) pouvant être logée de façon coulissante dans le tube de colonne. Le tube de colonne et la deuxième structure à cellule terminale sont séparées de manière à créer un espace d'accès entre ceux-ci. La partie piston (106) de la première structure à cellule terminale est avancée au travers du tube de colonne afin d'exposer ladite partie sur la deuxième extrémité ouverte du tube de colonne à des fins de maintenance de la partie piston ainsi exposée. L'invention concerne également un tel dispositif de chromatographie.

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