Chromatography purification of antibodies

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/00 (2006.01) A23J 1/00 (2006.01) B01D 15/10 (2006.01) C07K 1/16 (2006.01) C07K 1/22 (2006.01)

Patent

CA 2720615

Methods, kits and apparatuses for chromatography purification of antibodies are provided. In some embodiments, antibodies are purified by mixed mode chromatography that does not comprise hydroxyapatite (HT) or fluorapatite (FT). The mixed mode chromatography step is then followed by a HT/FT chromatography step.

L'invention concerne des procédés, kits et appareils de purification par chromatographie des anticorps. Dans certains modes de réalisation, les anticorps sont purifiés par une chromatographie en mode mixte ne comprenant pas en mode mixte est alors suivie d'une étape de chromatographie HT/FT.

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