Chromatogrpahic separation apparatus and method

Details Chromatogrpahic separation apparatus and method Chromatogrpahic separation apparatus and method

B - Operations, Transporting

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B01D 9/02 (2006.01) B01D 15/08 (2006.01) B01D 63/10 (2006.01) C07K 1/30 (2006.01) C07K 16/00 (2006.01) C12M 1/00 (2006.01) G01N 30/00 (2006.01)

Patent

CA 2363483

A fractionation apparatus comprises two channels coupled through a semi- permeable membrane. A time and position dependent concentration of precipitation reagent is produced in one of the channels. Sample entities such as macromolecules or cells introduced into this channel are eluted therefrom at different times depending on their solubility or mobility in the presence of the precipitation reagent.

L'invention concerne un appareil de fractionnement comportant deux voies couplées à une membrane semi-perméable. Le réactif de précipitation est produit dans une des voies. Son taux de concentration dépend de la période et du lieu. Des prélèvements d'entités tels que des macromolécules ou des cellules sont introduites dans cette voie puis éluées selon leur solubilité ou leur mobilité en présence du réactif de précipitation.

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