C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/00 (2006.01) A61K 31/335 (2006.01)
Patent
CA 2600797
The invention relates to small molecules which function as inhibitors of anti- apoptotic Bcl-2 family member proteins (e.g., Bcl-2 and Bcl-xL). The invention also relates to the use of these compounds for inducing apoptotic cell death and sensitizing cells to the induction of apoptotic cell death.
L'invention concerne de petites molécules servant d'inhibiteurs des protéines anti-apoptotiques de la famille Bcl-2 (par exemple Bcl-2 et Bcl-xL). L'invention concerne également l'utilisation de ces composés dans l'induction de la mort cellulaire apoptotique et la sensibilisation des cellules à l'induction de la mort cellulaire apoptotique.
Ding Ke
Nikolovska-Coleska Zaneta
Tang Guozhi
Wang Renxiao
Wang Shaomeng
Smart & Biggar
The Regents Of The University Of Michigan
LandOfFree
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