Chromene derivatives as anti-inflammatory agents

Details Chromene derivatives as anti-inflammatory agents Chromene derivatives as anti-inflammatory agents

C - Chemistry, Metallurgy

07

D

C07D 311/58 (2006.01) A61K 31/335 (2006.01) A61K 31/395 (2006.01) A61P 29/00 (2006.01) C07D 215/54 (2006.01) C07D 307/00 (2006.01) C07D 311/00 (2006.01) C07D 311/94 (2006.01) C07D 317/00 (2006.01) C07D 319/00 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/06 (2006.01) C07D 417/06 (2006.01) C07D 493/04 (2006.01)

Patent

CA 2519291

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula (I). Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.

La présente invention se rapporte à des procédés et des composés utilisables dans le traitement d'une pathologie associée à des troubles à médiation par cyclo-oxygénase-2. Parmi les composés présentant un intérêt particulier se trouvent les benzopyranes et leurs analogues définis par la formule I, dans laquelle Z, X, R?1¿, R?2¿, R?3¿ et R?4¿ ont la notation donnée dans la description.

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