C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
150/15.2, 150/3.
C07D 217/24 (2006.01) C07D 215/20 (2006.01) C07D 215/22 (2006.01) C07D 215/233 (2006.01) C07D 215/32 (2006.01) C07D 215/38 (2006.01) C07D 215/40 (2006.01) C07D 215/42 (2006.01) C07D 217/02 (2006.01) C12Q 1/37 (2006.01) C12Q 1/44 (2006.01)
Patent
CA 1272671
ABSTRACT OF THE DISCLOSURE: Novel acylaminic penicillinic antibiotics of general formula (I) and a method for their preparation are disclosed. In the general formula (I): Image (I) R has the following structure: Image or Image or Image wherein R3 is hydrogen, lower alkyl residue, lower alkoxycarbonyl residue or phenyl residue; R4, R5, R6 designates hydrogen, lower alkyl residue, halogen or lower alkoxyl residue; A is oxygen or N-lower alkyl residue; n takes values O or 1; R1 is hydrogen or hydroxyl group and R2 is hydrogen, alkaline metal or carboxy protective group. These antibiotics have a high antimicrobial activity against gram-positive and gram-negative microorganisms.
476410
Hugl Herbert
Runzheimer Hans-Volker
Schnabel Eugen
Wolfrum Gerhard
Hugl Herbert
Miles Laboratories Inc.
Osler Hoskin & Harcourt Llp
Runzheimer Hans-Volker
Schnabel Eugen
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