C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/5.04
C07K 5/08 (2006.01) C07K 5/083 (2006.01) C07K 5/087 (2006.01) C07K 5/097 (2006.01) C07K 5/10 (2006.01)
Patent
CA 1323726
Abstract of the disclosure Chromogenic compounds, a process for their preparation, and their use Compounds of the formula I Image (I) in which X denotes a hydrogen atom, a group which irreversibly masks the terminal amino group, or a protecting group which is conventional in peptide chemistry, such as, for example, Boc-, Z- or Fmoc-, A and B may be identical or different and denote an alpha-, beta- or gamma-amino acid which comprises 2 to 15 carbon atoms and up to 4 nitrogen atoms, 2 sulfur atoms and 6 oxygen atoms and whose side chain may be substituted, and B, if appropriate, denotes a dipep- tide formed from these amino acids, C denotes arginine, lysine, tyrosine, phenylalanine or tryptophane, and their homologs, R1 and R2 are identical or different and denote a hydrogen atom or an alkyl radical having up to 4 carbon atoms, R3 to R8 are identical or different and denote hydrogen, an alkyl radical, an alkoxy radical or a halogen radical, Y denotes oxygen, and An denotes an anion, and their water-soluble salts, and a process for their preparation are described. These compounds or salts can be used for detecting or deter- ?i?i?? enzymes
545487
Schnaitmann Dieter
Stuber Werner
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Dade Behring Marburg Gmbh
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