Chromogenic compounds, a process for their preparation and...

Details Chromogenic compounds, a process for their preparation and... Chromogenic compounds, a process for their preparation and...

C - Chemistry, Metallurgy

07

K

150/1, 150/15, 5

C07K 5/08 (2006.01) C07K 5/083 (2006.01) C07K 5/087 (2006.01) C07K 5/097 (2006.01) C07K 5/10 (2006.01) C07K 5/103 (2006.01) C07K 5/117 (2006.01) C07K 7/06 (2006.01) C12Q 1/37 (2006.01) C12Q 1/56 (2006.01)

Patent

CA 1268299

Abstract of the disclosure Chromogenic compounds of the formula I Image (I) and a process for their preparation are described, X denoting a hydrogen atom, a protective group customarily used in peptide chemistry or a group which irreversibly blocks the terminal amino group, A and P being identical or different and denoting an alpha-, beta- or gamma-amino acid which is com- posed of 2 to 15 carbon atoms with up to 3 nitro- gen atoms, 2 sulfur atoms and 6 oxygen atoms, and P also denoting a dipeptide formed from amino acids of these types, B denoting arginine, homoarginine, lysine, homo- lysine, ornithine or histidine and R denoting a substituent in the 2 or 3-position. The compounds can be used as substrates for the detection and the quantitative determination of hydroly- tic enzymes of enzyme class 3.4.21.

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