Chromogenic hemispherands and their use in detecting...

C - Chemistry – Metallurgy – 07 – D

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C07D 323/00 (2006.01) C07D 493/08 (2006.01) C07D 498/08 (2006.01) G01N 27/333 (2006.01) G01N 33/96 (2006.01)

Patent

CA 1300126

ABSTRACT OF THE DISCLOSURE The present invention resides in the discovery of a new class of compounds defined herein as "chromogenic hemispherands" useful for the measurement of ions, in particular, ions in aqueous solution, which have the structure Image wherein: R, same or different, is hydrogen, lower alkyl, lower alkylidene, lower alkenyl, allyl or aryl; R', same or different, is lower alkyl, lower alkylidene, lower alkenyl, allyl or aryl: Abstract Page 2 R", same or different, is hydrogen, lower alkyl, lower alkylidene, lower alkenyl, allyl or aryl; P is an aliphatic or aromatic subunit selected from the group consisting of -CR2CR2OCR2CR2-, Image and Image wherein R is as defined above; n is 0 to 3; m is 1 to 3; and Q is a chromogenic moiety capable of providing an appearance of or change in color, or other detectable response in the presence of a particular cation, and a buffer to provide a pH in the range of about 7 to 11.

560595

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